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Article

X-ray cross-complementing group 1 and thymidylate synthase polymorphisms might predict response to chemoradiotherapy in rectal cancer patients.

International journal of radiation oncology, biology, physics - 1 Jan 2012

Lamas Maria J, Duran Goretti, Gomez Antonio, Balboa Emilia, Anido Urbano, Bernardez Beatriz, Rana-Diez Pablo, Lopez Rafael, Carracedo Angel, Barros Francisco

Abstract excerpt

PURPOSE: 5-Fluorouracil-based chemoradiotherapy before total mesorectal excision is currently the standard treatment of Stage II and III rectal cancer patients. We used known predictive pharmacogenetic biomarkers to identify the responders to preoperative chemoradiotherapy in our series. METHODS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dihydrouracil Dehydrogenase (NADP)

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Source

Identifiers

PMID: 21167658
DOI: 10.1016/j.ijrobp.2010.09.053

Genes

XRCC1
TRG
EGFR
ERCC1
DPYD
MTHFR
TYMS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21167658-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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