Article
Thymidylate synthase genetic polymorphisms and colorectal cancer risk: a meta-analysis.
Clinics and research in hepatology and gastroenterology - 1 Sept 2014
Wang Jun, Shi Dengping, Guo Xufeng, Zhang Jixiang, Yu Shijie, Song Jia, Cao Zhuo, Wang Jing, Ji Mengyao, Dong Weiguo
Abstract excerpt
AIM: The effects of thymidylate synthase (TS) polymorphisms on susceptibility to colorectal cancer (CRC) have been investigated in many studies, but the results remain conflicting rather than conclusive. To resolve these conflicts, we performed a quantitative synthesis of the evidence on the association between these two polymorphisms and CRC risk. METHODS: All eligible case-control studies published up to...
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