Article
Role of glyoxalase I gene polymorphisms in late-onset epilepsy and drug-resistant epilepsy.
Journal of the neurological sciences - 15 Apr 2016
Tao Hua, Si Ligang, Zhou Xu, Liu Zhou, Ma Zhonghua, Zhou Haihong, Zhong Wangtao, Cui Lili, Zhang Shuyan, Li You, Ma Guoda, Zhao Jianghao, Huang Wenhui, Yao Lifen, Xu Zhien, Zhao Bin, Li Keshen
Abstract excerpt
BACKGROUND: Recent studies indicate that increased expression of glyoxalase I (GLO1) could result in epileptic seizures; thus, this study further explored the association of GLO1 with epilepsy from the perspective of molecular genetics. MATERIAL AND METHODS: GLO1 single nucleotide polymorphisms (SNPs; rs1130534, rs4746 and rs1049346) were investigated in cohort I (the initial samples: 249 cases and 289 controls)....
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