Article
Association between GLO1 variants and gestational diabetes mellitus susceptibility in a Chinese population: a preliminary study.
Frontiers in endocrinology - 1 Jan 2023
Zeng Qiaoli, Yang Taili, Wei Wenfeng, Zou Dehua, Wei Yue, Han Fengqiong, He Jieyun, Huang Jinzhi, Guo Runmin
Abstract excerpt
Background: Glyoxalase 1 (GLO1) plays a crucial role in defending against glycation. Single nucleotide polymorphism (SNP) variants in the GLO1 gene may affect gene expression and alter enzyme activity. However, there have been limited studies evaluating the association between GLO1 and diabetes, especially gestational diabetes mellitus (GDM). Therefore, this study is the first to explore the association of GLO1...
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