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Article

Glyoxalase I polymorphism rs2736654 causing the Ala111Glu substitution modulates enzyme activity--implications for autism.

Autism research : official journal of the International Society for Autism Research - 1 Aug 2011

Barua Madhabi, Jenkins Edmund C, Chen Wenqiang, Kuizon Salomon, Pullarkat Raju K, Junaid Mohammed A

Abstract excerpt

Autism is a pervasive, heterogeneous, neurodevelopmental disability characterized by impairments in verbal communications, reciprocal social interactions, and restricted repetitive stereotyped behaviors. Evidence suggests the involvement of multiple genetic factors in the etiology of autism, and extensive genome-wide association studies have revealed several candidate genes that bear single nucleotide...

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PMID: 21491613
DOI: 10.1002/aur.197
PMCID: PMC3138858

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Glyoxalase I polymorphism rs2736654 causing the Ala111Glu substitution modulates enzyme activity--implications for autism.PMID 21491613Read ↗

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