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Article

EAAT1 variants associated with glaucoma.

Biochemical and biophysical research communications - 3 Sept 2020

Yanagisawa Michiko, Namekata Kazuhiko, Aida Tomomi, Katou Sayaka, Takeda Takuya, Harada Takayuki, Fuse Nobuo, The Glaucoma Gene Research Group, Tanaka Kohichi

Abstract excerpt

Glaucoma is one of the leading causes of blindness characterized by progressive loss of retinal ganglion cells (RGCs) and their axons. We reported that glutamate/aspartate transporter (GLAST) knockout mice showed progressive RGC loss and optic nerve degeneration that are similar to glaucoma. To explore the possibility that rare variants in the EAAT1 gene (the human homolog of GLAST) cause susceptibility to...

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Share to Excitatory Amino Acid Transporter 1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mutation, Missense

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Source

Identifiers

PMID: 32819603
DOI: 10.1016/j.bbrc.2020.06.099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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