Article
Sequencing analysis of the human glucocorticoid receptor (NR3C1) gene in multiple sclerosis patients.
Journal of the neurological sciences - 15 Apr 2016
Kassi Eva, Semaniakou Anna, Sertedaki Amalia, Evangelopoulos Maria-Eleftheria, Kazazoglou Theodosia, Kominakis Antonios, Sfagos Constantinos, Charmandari Evangelia, Chrousos George P, Moutsatsou Paraskevi
Abstract excerpt
Various specific human glucocorticoid receptor (NR3C1) gene polymorphisms have been described in multiple sclerosis (MS) patients and correlated with disease progression, susceptibility and aggressiveness. Herein, we investigated the presence of gene alterations in the entire coding region of the NR3C1 in MS patients of variable clinical status (CIS, RRMS and SPMS) and the association(s) of these alterations with...
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