Article
Role of NR3C1 and GAS5 genes polymorphisms in multiple sclerosis.
The International journal of neuroscience - 1 Apr 2020
Moradi Mohsen, Gharesouran Jalal, Ghafouri-Fard Soudeh, Noroozi Rezvan, Talebian Shahrzad, Taheri Mohammad, Rezazadeh Maryam
Abstract excerpt
Introduction: Multiple sclerosis (MS) as a progressive chronic disease of the central nervous system (CNS) is characterized by demyelination and axonal loss. Results of genetic studies and clinical trials have proved a key role for the immune system in the pathogenesis of MS. Glucocorticoids (GR) are regarded as potent therapeutic compounds for autoimmune and inflammatory diseases which act through their...
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