Article
The role of functional single nucleotide polymorphisms of the human glucocorticoid receptor gene NR3C1 in Polish patients with bronchial asthma.
Molecular biology reports - 1 Apr 2012
Panek Michał, Pietras Tadeusz, Antczak Adam, Górski Paweł, Kuna Piotr, Szemraj Janusz
Abstract excerpt
N363S and ER22/23EK polymorphisms observed within glucocorticoid receptor gene (NR3C1) may play an important role in the development of bronchial asthma. NR3C1 gene is associated with an altered sensitivity to GCs. The aim of the research project was to study the correlation between this NR3C1 gene polymorphisms and occurrence of asthma in the population of Polish asthmatics. Peripheral blood was obtained from...
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