Article
The IL6R gene polymorphisms are associated with sIL-6R, IgE and lung function in Chinese patients with asthma.
Gene - 1 Jul 2016
Wang Yajun, Hu Huiting, Wu Jun, Zhao Xuanna, Zhen Yan, Wang Shaobing, Li Wen, Liang Min, Wu Bin, Ma Guoda
Abstract excerpt
BACKGROUND: sIL-6R is involved in a variety of inflammatory diseases. The present study analyzed the potential associations between two IL6R gene polymorphisms (rs2228145 and rs12083537) and asthma in a Han Chinese population. METHODS: A cohort of 394 patients and 395 healthy controls were genotyped to detect the two polymorphisms using SNaPshot. In 66 asthma patients and 49 controls, peripheral eosinophil and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.