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IL6R gene polymorphisms and their relation to chronic obstructive pulmonary disease susceptibility in the Chinese population.

Biomarkers in medicine - 1 Dec 2022

Wu Haihong, He Chanyi, Fu Yihui, Li Xiukuan, Zheng Yamei, Mo Rubing, Zhang Lei, Zhao Jie, Zhang Bingli, Lin Qi, Xie Tian, Ding Yipeng

Abstract excerpt

Background: This work was designed to explore the correlation between IL6R polymorphisms and chronic obstructive pulmonary disease (COPD) susceptibility. Methods: Agena MassARRAY was used to genotype five SNPs of IL6R in 498 patients with COPD and 498 controls. Genetic models and haplotype analysis were used to assess the associations between SNPs and COPD risk. Results: Rs6689306 and rs4845625 increase the risk...

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PMID: 36809146
DOI: 10.2217/bmm-2022-0342

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