Genomic Subclassification and Risk Stratification of ALL.

Abstract excerpt

BACKGROUND: Over the last 2 decades, significant improvements have been made in the understanding of the genomic and biological bases of acute lymphoblastic leukemia (ALL), resulting in enhanced genomic classification, more precise risk stratification, and improved long-term outcomes. ALL is a hematologic malignancy defined by uncontrolled proliferation of immature B- or T-lymphoid blasts in the bone marrow,...

Topics

• Humans
• Precursor Cell Lymphoblastic Leukemia-Lymphoma
• Genomics
• Chromosome Aberrations
• Risk Assessment
• Prognosis
• Mutation