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Article

Generation of Infectious Poliovirus with Altered Genetic Information from Cloned cDNA.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016

Bujaki Erika

Abstract excerpt

The effect of specific genetic alterations on virus biology and phenotype can be studied by a great number of available assays. The following method describes the basic protocol to generate infectious poliovirus with altered genetic information from cloned cDNA in cultured cells.The example explained here involves generation of a recombinant poliovirus genome by simply replacing a portion of the 5' noncoding...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 26983738
DOI: 10.1007/978-1-4939-3292-4_12

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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