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Article

Molecular genetics of DNA viruses: recombinant virus technology.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2005

Neuhierl Bernhard, Delecluse Henri-Jacques

Abstract excerpt

Recombinant viral genomes cloned onto BAC vectors can be subjected to extensive molecular genetic analysis in the context of E. coli. Thus, the recombinant virus technology exploits the power of prokaryotic genetics to introduce all kinds of mutations into the recombinant genome. All available techniques are based on homologous recombination between a targeting vector carrying the mutated version of the gene of...

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PMID: 15507720
DOI: 10.1385/1-59259-848-x:353

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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