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A decade after the generation of a negative-sense RNA virus from cloned cDNA – what have we learned?

1 Nov 2002

Abstract excerpt

Since the first generation of a negative-sense RNA virus entirely from cloned cDNA in 1994, similar reverse genetics systems have been established for members of most genera of the Rhabdo- and Paramyxoviridae families, as well as for Ebola virus (Filoviridae). The generation of segmented negative-sense RNA viruses was technically more challenging and has lagged behind the recovery of nonsegmented viruses,...

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PMID: 12388800
DOI: 10.1099/0022-1317-83-11-2635

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