Article

Efficient plasmid-based rescue of T7 RNA polymerase-driven calicivirus reverse genetics systems in mammalian cells using vaccinia virus RNA capping enzymes

2026-03-19

Abstract excerpt

The caliciviruses include important human and animal pathogens such as norovirus, sapovirus and feline calicivirus. Viral reverse genetics is performed to understand the fundamental biology of these viruses, as well as a potential route to generate live-attenuated vaccines. Calicivirus reverse genetics systems have typically relied on either on the production of in vitro- transcribed RNA or plasmid-based rescue e...

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Literature Corpus work: f523541a-c044-5d08-a37e-abce43f20d31
DOI: 10.64898/2026.03.19.712921

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