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Article

A two-locus system controls susceptibility to colitis-associated colon cancer in mice.

Oncotarget - 1 Oct 2010

Van Der Kraak Lauren, Meunier Charles, Turbide Claire, Jothy Serge, Gaboury Louis, Marcus Victoria, Chang Sing Yun, Beauchemin Nicole, Gros Philippe

Abstract excerpt

We have previously shown that the differential susceptibility of A/J (susceptible) and C57BL/6J (B6, resistant) mouse strains to azoxymethane (AOM)-induced colorectal cancer (CRC) is controlled by the chromosome 3 locus, Ccs3. We report that A/J and B6 mice also show differential susceptibility to colitis-associated colorectal cancer (CA-CRC) induced by combined administration of AOM and dextran sulfate. This...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21311099
DOI: 10.18632/oncotarget.177
PMCID: PMC3248117

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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