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Article

Hepatitis C virus quasispecies and pseudotype analysis from acute infection to chronicity in HIV-1 co-infected individuals.

Virology - 1 May 2016

Ferns R Bridget, Tarr Alexander W, Hue Stephane, Urbanowicz Richard A, McClure C Patrick, Gilson Richard, Ball Jonathan K, Nastouli Eleni, Garson Jeremy A, Pillay Deenan

Abstract excerpt

HIV-1 infected patients who acquire HCV infection have higher rates of chronicity and liver disease progression than patients with HCV mono-infection. Understanding early events in this pathogenic process is important. We applied single genome sequencing of the E1 to NS3 regions and viral pseudotype neutralization assays to explore the consequences of viral quasispecies evolution from pre-seroconversion to...

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Identifiers

PMID: 26971243
DOI: 10.1016/j.virol.2016.02.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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