Article
Diversity of the hepatitis C virus NS5B gene during HIV co-infection.
PloS one - 1 Jan 2020
Ngwaga Tshegofatso, Kong Ling, Lin Derrick, Schoborg Cassandra, Taylor Lynn E, Mayer Kenneth H, Klein Robert S, Celentano David D, Sobel Jack D, Jamieson Denise J, King Caroline C, Tavis John E, Blackard Jason T
Abstract excerpt
Viral diversity is an important feature of hepatitis C virus (HCV) infection and an important predictor of disease progression and treatment response. HIV/HCV co-infection is associated with enhanced HCV replication, increased fibrosis, and the development of liver disease. HIV also increases quasispecies diversity of HCV structural genes, although limited data are available regarding the impact of HIV on...
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