Article
Understanding Basic Concepts of Viral Quasispecies: From Evolutionary Dynamics to Clinical Relevance.
Pathogens (Basel, Switzerland) - 5 Aug 2026
Rodríguez-Frías Francisco, Oubiña José Raúl, Tabernero David, Cortese Maria Francesca, Gregori Josep, Buti Maria, Rando-Segura Ariadna, Quer Josep
Abstract excerpt
This review examines the viral quasispecies concept and its implications for understanding viral evolution, pathogenesis, and the development of effective antiviral therapies. Quasispecies are dynamic populations of closely related but genetically distinct viral genomes, which evolve under mutation and Darwinian selection. Notably, minority variants, often dismissed as "genetic noise", may harbor significant...
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