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Article

Hepatitis C virus continuously escapes from neutralizing antibody and T-cell responses during chronic infection in vivo.

Gastroenterology - 1 Feb 2007

von Hahn Thomas, Yoon Joo Chun, Alter Harvey, Rice Charles M, Rehermann Barbara, Balfe Peter, McKeating Jane A

Abstract excerpt

BACKGROUND & AIMS: Broadly reactive neutralizing antibodies (nAbs) and multispecific T-cell responses are generated during chronic hepatitis C virus (HCV) infection and yet fail to clear the virus. This study investigated the development of autologous nAb and HCV-glycoprotein-specific T-cell responses and their effects on viral sequence evolution during chronic infection in order to understand the reasons for...

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Source

Identifiers

PMID: 17258731
DOI: 10.1053/j.gastro.2006.12.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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