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Article

Age, APOE and sex: Triad of risk of Alzheimer's disease.

The Journal of steroid biochemistry and molecular biology - 1 Jun 2016

Riedel Brandalyn C, Thompson Paul M, Brinton Roberta Diaz

Abstract excerpt

Age, apolipoprotein E ε4 (APOE) and chromosomal sex are well-established risk factors for late-onset Alzheimer's disease (LOAD; AD). Over 60% of persons with AD harbor at least one APOE-ε4 allele. The sex-based prevalence of AD is well documented with over 60% of persons with AD being female. Evidence indicates that the APOE-ε4 risk for AD is greater in women than men, which is particularly evident in...

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Aging
Alzheimer Disease
Apolipoprotein E4
Cholesterol
Homozygote
Menopause

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Molecular

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Identifiers

PMID: 26969397
DOI: 10.1016/j.jsbmb.2016.03.012
PMCID: PMC4905558

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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