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Article

Associations between a locus downstream DRD1 gene and cerebrospinal fluid dopamine metabolite concentrations in psychosis.

Neuroscience letters - 21 Apr 2016

Andreou Dimitrios, Söderman Erik, Axelsson Tomas, Sedvall Göran C, Terenius Lars, Agartz Ingrid, Jönsson Erik G

Abstract excerpt

Dopamine activity, mediated by the catecholaminergic neurotransmitter dopamine, is prominent in the human brain and has been implicated in schizophrenia. Dopamine targets five different receptors and is then degraded to its major metabolite homovanillic acid (HVA). We hypothesized that genes encoding dopamine receptors may be associated with cerebrospinal fluid (CSF) HVA concentrations in patients with psychotic...

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Source

Identifiers

PMID: 26957229
DOI: 10.1016/j.neulet.2016.03.005

Genes

DRD1
DRD2
DRD3
DRD4
DRD5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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