Article
DRD4 dopamine receptor genotype and CSF monoamine metabolites in Finnish alcoholics and controls.
American journal of medical genetics - 19 Jun 1995
Adamson M D, Kennedy J, Petronis A, Dean M, Virkkunen M, Linnoila M, Goldman D
Abstract excerpt
The DRD4 dopamine receptor is thus far unique among neurotransmitter receptors in having a highly polymorphic gene structure that has been reported to produce altered receptor functioning. These allelic variations are caused by a 48-bp segment in exon III of the coding region which may be repeated from 2-10 times. Varying the numbers of repeated segments changes the length, structure, and, possibly, the...
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