Association of Genetic Variants of Dopamine and Serotonin In Schizophrenia.

doi:10.1016/j.arcmed.2019.12.011

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Article

Association of Genetic Variants of Dopamine and Serotonin In Schizophrenia.

Archives of medical research - 1 Jan 2020

Zakharyan Roksana, Ghazaryan Hovsep, Kocourkova Lenka, Chavushyan Andranik, Mkrtchyan Artur, Zizkova Veronika, Arakelyan Arsen, Petrek Martin

Abstract excerpt

BACKGROUND: Several studies indicated that antipsychotic treatment response and side effect manifestation can be different due to inter-individual variability in genetic variations. AIM OF THE STUDY: Here we perform a case-control study to explore a potential association between schizophrenia and variants within the antipsychotic drug molecular targets (DRD1, DRD2, DRD3, HTR2A, HTR6) and metabolizing enzymes...

Topics

Adult
Aged
Antipsychotic Agents
Case-Control Studies
Catechol O-Methyltransferase
Cytochrome P-450 CYP2D6
Dopamine
Female
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Humans

Male

Metabolic Networks and Pathways

Middle Aged

Polymorphism, Single Nucleotide

Receptors, Dopamine

Source

Open in PubMed

Identifiers

PMID: 32086104
DOI: 10.1016/j.arcmed.2019.12.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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