Article
Dystrobrevin-binding protein 1 gene (DTNBP1) variants associated with cerebrospinal fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in healthy volunteers.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Sept 2011
Andreou Dimitrios, Saetre Peter, Kähler Anna K, Werge Thomas, Andreassen Ole A, Agartz Ingrid, Sedvall Göran C, Hall Håkan, Terenius Lars, Jönsson Erik G
Abstract excerpt
The dystrobrevin binding protein-1 (DTNBP1) gene encodes dysbindin-1, a protein involved in neurodevelopmental and neurochemical processes related mainly to the monoamine dopamine. We investigated possible associations between eleven DTNBP1 polymorphisms and cerebrospinal fluid (CSF) concentrations of the major dopamine metabolite homovanillic acid (HVA), the major serotonin metabolite 5-hydroxyindoleacetic acid...
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