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Article

D-amino acid oxidase activator gene (DAOA) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy Caucasians.

European archives of psychiatry and clinical neuroscience - 1 Oct 2012

Andreou Dimitrios, Saetre Peter, Werge Thomas, Andreassen Ole A, Agartz Ingrid, Sedvall Göran C, Hall Håkan, Terenius Lars, Jönsson Erik G

Abstract excerpt

The D-amino acid oxidase activator (DAOA) protein regulates the function of D-amino oxidase (DAO), an enzyme that catalyzes the oxidative deamination of D-3,4-dihydroxyphenylalanine (D-DOPA) and D-serine. D-DOPA is converted to L-3,4-DOPA, a precursor of dopamine, whereas D-serine participates in glutamatergic transmission. We hypothesized that DAOA polymorphisms are associated with dopamine, serotonin and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22454242
DOI: 10.1007/s00406-012-0313-z
PMCID: PMC3464385

Genes

DAOA
DAO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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