Genetic contribution of CYP1A1 variant on treatment outcome in epilepsy patients: a functional and interethnic perspective.

doi:10.1038/tpj.2016.1

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Article

Genetic contribution of CYP1A1 variant on treatment outcome in epilepsy patients: a functional and interethnic perspective.

The pharmacogenomics journal - 1 Jun 2017

Talwar P, Kanojia N, Mahendru S, Baghel R, Grover S, Arora G, Grewal G K, Parween S, Srivastava A, Singh M, Vig S, Kushwaha S, Sharma S, Bala K, Kukreti S, Kukreti R

Abstract excerpt

CYP1A1 gene is involved in estrogen metabolism, and previously, we have reported association of variant rs2606345 with altered anti-epileptic drugs (AED) response in North Indian women with epilepsy (WWE). The present study aims to replicate the pharmacogenetic association, perform functional characterization and study its distribution within ethnically diverse Indian population. The variant was genotyped in 351...

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PMID: 26951882
DOI: 10.1038/tpj.2016.1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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