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Article

Pharmacogenetic insights into ABCB1, ABCC2, CYP1A2, and CYP2B6 variants with epilepsy susceptibility among Egyptian Children: A retrospective case-control study.

International immunopharmacology - 5 Dec 2024

Attia Zeinab R, Labib Mariam E, Kelany Ayda K, Alnefaie Rasha M, Twab Hosam Abd, Wahsh Eman, Abd El Azeem Rania A, Shaaban Esraa Ibrahim A, Elsaid Afaf M, Alalawy Adel I, Elshazli Rami M, El Tantawi Noha

Abstract excerpt

BACKGROUND: Pediatric epilepsy is a complicated neuropsychiatric disorder that is characterized by recurrent seizures and unusual synchronized electrical activities within brain tissues. It has a substantial effect on the quality of life of children, thus understanding of the hereditary considerations influencing epilepsy susceptibility and the response to antiepileptic medications is crucial. This study focuses...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39265352
DOI: 10.1016/j.intimp.2024.113073

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