Article
Genetic polymorphisms of CYP2E1 and GSTP1 in a South Indian population--comparison with North Indians, Caucasians and Chinese.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2000
Soya S S, Padmaja N, Adithan C
Abstract excerpt
CYP2E1 and GSTP1 enzymes belong to phase I and phase II group of drug metabolizing enzymes respectively which are involved in the metabolic activation and detoxification of various potential genotoxic compounds. The functional polymorphism in these genes exhibit inter-individual variations in susceptibility towards various diseases and difference in therapeutic response. The variant sequences of these genes...
Topics
- Adult
- China
- Cytochrome P-450 CYP2E1
- DNA Mutational Analysis
- Ethnicity
- Female
- Genotype
- Glutathione S-Transferase pi
- Humans
- India
- Male
- Middle Aged
- Neoplasms
- Polymorphism, Genetic
- White People
