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Polymorphisms Affecting the Response to Novel Antiepileptic Drugs.

International journal of molecular sciences - 28 Jan 2023

Urzì Brancati Valentina, Pinto Vraca Tiziana, Minutoli Letteria, Pallio Giovanni

Abstract excerpt

Epilepsy is one of the most frequent chronic neurologic disorders that affects nearly 1% of the population worldwide, especially in developing countries. Currently, several antiepileptic drugs (AEDs) are available for its therapy, and although the prognosis is good for most patients, 20%-30% amongst them do not reach seizure freedom. Numerous factors may explain AED-resistance such as sex, age, ethnicity, type of...

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Anticonvulsants
Drug Resistance
Drug Transport and Resistance Mechanisms
Epilepsy
Epilepsy research and treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pharmacogenetics

Pharmacological Effects and Toxicity Studies

Polymorphism, Single Nucleotide

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Identifiers

PMID: 36768858
DOI: 10.3390/ijms24032535
PMCID: PMC9917302

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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