Article
Polymorphisms Affecting the Response to Novel Antiepileptic Drugs.
International journal of molecular sciences - 28 Jan 2023
Urzì Brancati Valentina, Pinto Vraca Tiziana, Minutoli Letteria, Pallio Giovanni
Abstract excerpt
Epilepsy is one of the most frequent chronic neurologic disorders that affects nearly 1% of the population worldwide, especially in developing countries. Currently, several antiepileptic drugs (AEDs) are available for its therapy, and although the prognosis is good for most patients, 20%-30% amongst them do not reach seizure freedom. Numerous factors may explain AED-resistance such as sex, age, ethnicity, type of...
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