Polymorphisms of genes encoding interleukin-4 and its receptor in Iranian patients with juvenile idiopathic arthritis.

doi:10.1007/s10067-016-3224-y

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Article

Polymorphisms of genes encoding interleukin-4 and its receptor in Iranian patients with juvenile idiopathic arthritis.

Clinical rheumatology - 1 Aug 2016

Ziaee Vahid, Rezaei Arezou, Harsini Sara, Maddah Marzieh, Zoghi Samaneh, Sadr Maryam, Moradinejad Mohammad Hassan, Rezaei Nima

Abstract excerpt

As cytokines, including interleukin-4 (IL-4), seem to have a pivotal role in the pathogenesis of juvenile idiopathic arthritis (JIA), this study is aimed at investigating of association of polymorphisms in IL-4 and IL-4 receptor α (IL-4RA) genes with susceptibility to JIA. A case-control study wa...

Topics

Adolescent
Alleles
Arthritis, Juvenile
Case-Control Studies
Child
Child, Preschool
Female
Gene Frequency
Genetic Predisposition to Disease
Haplotypes
Humans
Interleukin-4
Interleukin-4 Receptor alpha Subunit
Iran
Male
Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 26951255
DOI: 10.1007/s10067-016-3224-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-26951255-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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