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Article

Association of interleukin-4 receptor gene polymorphisms with rheumatoid arthritis in Egyptian female patients.

Joint bone spine - 1 Jan 2012

Hussein Yousri, El-Tarhouny Shereen, Mohamed Randa, Pasha Heba, Abul-Saoud Amany

Abstract excerpt

OBJECTIVES: The imbalance between proinflammatory and anti-inflammatory cytokines is a feature of rheumatoid arthritis (RA). The role of interleukin-4 (IL-4) and its receptor in the pathogenesis of RA is conflicting. We aim to investigate the role of polymorphisms in the IL-4Rα gene in susceptibility and severity of RA. METHODS: One hundred and seventy-two RA patients and 172 controls were enrolled in the study....

Topics

Adult
Aged
Arthritis, Rheumatoid
DNA
Egypt
Female
Genetic Predisposition to Disease
Genotype
Health Status
Humans
Interleukin-4 Receptor alpha Subunit

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Polymorphism, Genetic

Severity of Illness Index

Source

Identifiers

PMID: 21497535
DOI: 10.1016/j.jbspin.2011.02.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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