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Article

Circulating T follicular helper cells with increased function during chronic graft-versus-host disease

5 Mar 2016

Abstract excerpt

Chronic graft-versus-host disease (cGVHD) remains a major late complication of allogeneic hematopoietic stem cell transplantation (HSCT). Previous studies have established that both donor B and T cells contribute to immune pathology in cGVHD but the mechanisms responsible for coordinated B- and T-cell responses directed against recipient antigens have not been understood. T follicular helper cells (TFH) play an...

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PMID: 26944544
DOI: 10.1182/blood-2015-12-688895

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