Article
Comparative analysis of FoxP3(+) regulatory T cells in the target tissues and blood in chronic graft versus host disease.
Leukemia - 1 Oct 2014
Imanguli M M, Cowen E W, Rose J, Dhamala S, Swaim W, Lafond S, Yagi B, Gress R E, Pavletic S Z, Hakim F T
Abstract excerpt
Activation and migration of regulatory T cells (Treg) into tissue is critical in control of inflammation, but has not been examined extensively in chronic graft versus host disease (cGVHD). In parallel studies of tissues and blood, we determined that FoxP3(+) T cells increased in proportion to T effectors (Teff) in tissue infiltrates in oral and cutaneous lichenoid cGVHD. These FoxP3(+) cells expressed...
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