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Article

Aberrant B-cell homeostasis in chronic GVHD

2 Feb 2015

Abstract excerpt

Recent studies have compelled further interest in the potential pathological role of B cells in chronic graft-versus-host disease (cGVHD). In patients with cGVHD, B cells are activated and primed for survival via B-cell activating factor and B-cell receptor-associated pathways. Understanding the signaling pathways that drive immune pathology in cGVHD will facilitate the development of new strategies to...

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PMID: 25645355
DOI: 10.1182/blood-2014-12-567834

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