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Article

CRISPR-Cas9: a promising tool for gene editing on induced pluripotent stem cells.

The Korean journal of internal medicine - 1 Jan 2017

Kim Eun Ji, Kang Ki Ho, Ju Ji Hyeon

Abstract excerpt

Recent advances in genome editing with programmable nucleases have opened up new avenues for multiple applications, from basic research to clinical therapy. The ease of use of the technology-and particularly clustered regularly interspaced short palindromic repeats (CRISPR)-will allow us to improve our understanding of genomic variation in disease processes via cellular and animal models. Here, we highlight the...

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Identifiers

PMID: 28049282
DOI: 10.3904/kjim.2016.198
PMCID: PMC5214730

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