Article
The role of G protein-coupled receptors in cochlear planar cell polarity.
The international journal of biochemistry & cell biology - 1 Aug 2016
Sun Jinpeng, Zhang Daolai, Wang Yanfei, Lin Hal, Yu Xiao, Xu Zhigang
Abstract excerpt
Planar cell polarity (PCP) is defined as the coordinated alignment of cell polarity across the tissue plane, which is important for the integration of cells into tissues. One of the best examples of PCP is in the cochlear epithelium. Several core PCP proteins have been identified to play important roles in PCP regulation, in which these proteins form complexes and associate with the cell membrane asymmetrically,...
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