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Article

Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochlea

20 Jan 2015

Abstract excerpt

Primary cilia have been implicated in the generation of planar cell polarity (PCP). However, variations in the severity of polarity defects in different cilia mutants, coupled with recent demonstrations of non-cilia-related actions of some cilia genes, make it difficult to determine the basis of these polarity defects. To address this issue, we evaluated PCP defects in cochlea from a selection of mice with...

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PMID: 25605782
DOI: 10.1242/dev.113696

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