Article
Mouse models for dissecting vertebrate planar cell polarity signaling in the inner ear.
Brain research - 24 Jun 2009
Chacon-Heszele Maria F, Chen Ping
Abstract excerpt
Planar cell polarity (PCP) refers to coordinated polarization of cells in the plane of a cell sheet. In Drosophila, the stereotypical arrangement of the eight photoreceptor cells in each of the ommatidia of the fly compound eye and the uniform orientation of the hairs in all the wing cells are two representative forms of PCP. Using these powerful Drosophila model systems, a set of genes was identified to...
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