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Article

PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates.

Nature - 1 Jul 2004

Lu Xiaowei, Borchers Annette G M, Jolicoeur Christine, Rayburn Helen, Baker Julie C, Tessier-Lavigne Marc

Abstract excerpt

In addition to the apical-basal polarity pathway operating in epithelial cells, a planar cell polarity (PCP) pathway establishes polarity within the plane of epithelial tissues and is conserved from Drosophila to mammals. In Drosophila, a 'core' group of PCP genes including frizzled (fz), flamingo/starry night, dishevelled (dsh), Van Gogh/strabismus and prickle, function to regulate wing hair, bristle and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15229603
DOI: 10.1038/nature02677

Genes

PTK7
CCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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