Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Angiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life Span.

PLoS genetics - 1 Feb 2016

Kumar Sandeep, Dietrich Nicholas, Kornfeld Kerry

Abstract excerpt

Animal aging is characterized by progressive, degenerative changes in many organ systems. Because age-related degeneration is a major contributor to disability and death in humans, treatments that delay age-related degeneration are desirable. However, no drugs that delay normal human aging are currently available. To identify drugs that delay age-related degeneration, we used the powerful Caenorhabditis elegans...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin-Converting Enzyme Inhibitors
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electron Transport Complex III

Share to Forkhead Transcription Factors

Share to Longevity

Share to Phosphatidylinositol 3-Kinases

Share to Receptor, Insulin

Share to Sirtuins

Source

Open in PubMed Open full text

Identifiers

PMID: 26918946
DOI: 10.1371/journal.pgen.1005866
PMCID: PMC4769152

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Angiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life Span.PMID 26918946Read ↗

The ACE inhibitor captopril inhibits ACN-1 to control dauer formation and aging.Semantic proximity Read ↗

The ACE-inhibitor drug captopril inhibits ACN-1 to control dauer formation and agingSemantic proximity Read ↗

Caenorhabditis elegans as a Useful Model for Studying Aging Mutations.Semantic proximity Read ↗

Caenorhabditis elegans 2007: the premier model for the study of aging.Semantic proximity Read ↗

End-of-life targeted degradation of DAF-2 insulin/IGF-1 receptor promotes longevity free from growth-related pathologies.Semantic proximity Read ↗

Longevity determined by developmental arrest genes in Caenorhabditis elegans.Semantic proximity Read ↗

Using Caenorhabditis elegans as a model for aging and age-related diseases.Semantic proximity Read ↗

Genetics, life span, health span, and the aging process in Caenorhabditis elegans.Semantic proximity Read ↗

End-of-life targeted auxin-mediated degradation of DAF-2 Insulin/IGF-1 receptor promotes longevity free from growth-related pathologiesSemantic proximity Read ↗

Caenorhabditis elegans as a model system for human diseases.Semantic proximity Read ↗

Curcumin-mediated lifespan extension in Caenorhabditis elegans.Semantic proximity Read ↗

Icariin Improves Stress Resistance and Extends Lifespan in Caenorhabditis elegans through hsf-1 and daf-2-Driven HormesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.