Article
Caenorhabditis elegans as a model system for human diseases.
Current opinion in biotechnology - 1 Jun 2020
Markaki Maria, Tavernarakis Nektarios
Abstract excerpt
The nematode Caenorhabditis elegans offers unique advantages that enable a comprehensive delineation of the cellular and molecular mechanisms underlying devastating human pathologies such as stroke, ischemia and age-associated neurodegenerative disorders. Genetic models of human diseases that closely simulate several disease-related phenotypes have been established in the worm. These models allow the...
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