Article
Whole genome sequencing to complement tuberculosis drug resistance surveys in Uganda.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2016
Ssengooba Willy, Meehan Conor J, Lukoye Deus, Kasule George William, Musisi Kenneth, Joloba Moses L, Cobelens Frank G, de Jong Bouke C
Abstract excerpt
Understanding the circulating Mycobacterium tuberculosis resistance mutations is vital for better TB control strategies, especially to inform a new MDR-TB treatment programme. We complemented the phenotypic drug susceptibility testing (DST) based drug resistance surveys (DRSs) conducted in Uganda between 2008 and 2011 with Whole Genome Sequencing (WGS) of 90 Mycobacterium tuberculosis isolates phenotypically...
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