Article

Whole Genome Sequencing of Clinical Samples Reveals Extensively Drug Resistant Tuberculosis (XDR TB) Strains From The Beijing Lineage in Nigeria, West Africa.

2021-07-20

Abstract excerpt

Multi-drug (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) continues to be a global public health problem especially in high TB burden countries like Nigeria. Many of these cases are undetected and go on to infect high risk individuals. Clinical samples from positive rifampicin resistant Xpert®MTB/Rif assay were subjected to direct whole genome sequencing and bioinformatics analysis to identify the fu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2a4ea666-18c7-5499-9dab-a5d94bd19c13
DOI: 10.21203/rs.3.rs-678617/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Whole Genome Sequencing of Clinical Samples Reveals Extensively Drug Resistant Tuberculosis (XDR TB) Strains From The Beijing Lineage in Nigeria, West Africa.DOI 10.21203/rs.3.rs-678617/v1Read

Exploration of the diversity of multi-drug resistant Mycobacterium tuberculosis complex in Lagos, Nigeria using WGS: Distribution of lineages, drug resistance patterns and genetic mutations.Semantic proximity Read

Whole genome sequencing of Mycobacterium tuberculosis isolates and clinical outcomes of patients treated for multidrug-resistant tuberculosis in Tanzania.Semantic proximity Read

Whole genome sequencing of drug resistant Mycobacterium tuberculosis isolates from a high burden tuberculosis region of North West PakistanSemantic proximity Read

Clinical application of whole-genome sequencing in the management of extensively drug-resistant tuberculosis: a case report.Semantic proximity Read

Mycobacterium tuberculosis complex drug-resistance, phylogenetics, and evolution in Nigeria: Comparison with Ghana and Cameroon.Semantic proximity Read

Whole Genome Sequencing of Drug Resistant and Drug Susceptible Mycobacterium tuberculosis Isolates From Tigray Region, EthiopiaSemantic proximity Read

Whole-Genome Sequencing to Predict Mycobacterium tuberculosis Drug Resistance: A Retrospective Observational Study in Eastern ChinaSemantic proximity Read

Whole genome sequencing-based detection of extensively drug-resistant tuberculosis from EthiopiaSemantic proximity Read

Whole-genome sequencing of clinical isolates from tuberculosis patients in India: real-world data indicates a high proportion of pre-XDR cases.Semantic proximity Read

Genotypic drug resistance using whole-genome sequencing of Mycobacterium tuberculosis clinical isolates from North-western Tanzania.Semantic proximity Read

Whole-genome sequencing of presumptive MDR-TB isolates from a tertiary healthcare setting in MumbaiSemantic proximity Read

Unearthing novel mutations and genetic variation in drug sensitive and resistant isolates of Mycobacterium tuberculosis through whole genome sequencing: A study from eastern Uttar Pradesh, India.Semantic proximity Read