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Article

Clinical application of whole-genome sequencing in the management of extensively drug-resistant tuberculosis: a case report.

Annals of clinical microbiology and antimicrobials - 22 Aug 2024

Katale Bugwesa Z, Rofael Sylvia, Elton Linzy, Mbugi Erasto V, Mpagama Stella G, Mtunga Daphne, Mafie Maryjesca G, Mbelele Peter M, Williams Charlotte, Mvungi Happiness C, Williams Rachel, Saku Gulinja A, Ruta Joanitha A, McHugh Timothy D, Matee Mecky I

Abstract excerpt

BACKGROUND: Whole-genome sequencing (WGS)-based prediction of drug resistance in Mycobacterium tuberculosis has the potential to guide clinical decisions in the design of optimal treatment regimens. METHODS: We utilized WGS to investigate drug resistance mutations in a 32-year-old Tanzanian male admitted to Kibong'oto Infectious Diseases Hospital with a history of interrupted multidrug-resistant tuberculosis...

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Identifiers

PMID: 39175078
DOI: 10.1186/s12941-024-00737-9
PMCID: PMC11342570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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