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Article

PON1 as a model for integration of genetic, epigenetic, and expression data on candidate susceptibility genes

1 Jan 2015

Abstract excerpt

Recent genome- and epigenome-wide studies demonstrate that the DNA methylation is controlled in part by genetics, highlighting the importance of integrating genetic and epigenetic data. To better understand molecular mechanisms affecting gene expression, we used the candidate susceptibility gene paraoxonase 1 (PON1) as a model to assess associations of PON1 genetic polymorphisms with DNA methylation and...

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PMID: 26913202
DOI: 10.1093/eep/dvv003

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