Article
Activation of the cryptic PhnE permease promotes rapid adaptive evolution in a population of Escherichia coli K-12 starved for phosphate.
Journal of bacteriology - 1 Jan 2012
Guillemet Mélanie L, Moreau Patrice L
Abstract excerpt
Escherichia coli K-12 suffers acetic acid stress during prolonged incubation in glucose minimal medium containing a limiting concentration of inorganic phosphate (0.1 mM P(i)), which decreases the number of viable cells from 6 × 10(8) to ≤10 CFU/ml between days 6 and 14 of incubation. Here we show that following two serial transfers into P(i)-limiting medium, evolved mutants survived prolonged incubation (≈10(7)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
