Article
Deletion of the 2-acyl-glycerophosphoethanolamine cycle improve glucose metabolism in Escherichia coli strains employed for overproduction of aromatic compounds.
Microbial cell factories - 1 Dec 2015
Aguilar César, Flores Noemí, Riveros-McKay Fernando, Sahonero-Canavesi Diana, Carmona Susy Beatriz, Geiger Otto, Escalante Adelfo, Bolívar Francisco
Abstract excerpt
BACKGROUND: As a metabolic engineering tool, an adaptive laboratory evolution (ALE) experiment was performed to increase the specific growth rate (µ) in an Escherichia coli strain lacking PTS, originally engineered to increase the availability of intracellular phosphoenolpyruvate and redirect to the aromatic biosynthesis pathway. As result, several evolved strains increased their growth fitness on glucose as the...
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