Article
The risk of new-onset cancer associated with HFE C282Y and H63D mutations: evidence from 87,028 participants.
Journal of cellular and molecular medicine - 1 Jul 2016
Lv Yang-Fan, Chang Xian, Hua Rui-Xi, Yan Guang-Ning, Meng Gang, Liao Xiao-Yu, Zhang Xi, Guo Qiao-Nan
Abstract excerpt
To investigate the association between mutation of HFE (the principal pathogenic gene in hereditary haemochromatosis) and risk of cancer, we conducted a meta-analysis of all available case-control or cohort studies relating to two missense mutations, C282Y and H63D mutations. Eligible studies were identified by searching databases including PubMed, Embase and the ISI Web of Knowledge. Overall and subgroup...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.